Oh, honey, if you’re looking for a dish that’ll warm you up from the inside out, my Sausage Pasta with Brussels Sprouts and Butternut Squash is just the ticket. This is the kind of meal I’ve been making for Sunday suppers for years – it’s got everything you want in one glorious skillet. The sweet roasted squash, those crispy Brussels sprouts, smoky sausage, and pasta all swimming in garlic butter? Goodness gracious, it’s like all the best parts of fall on a plate.

Table of Contents
Table of Contents
Now don’t let the fancy-sounding name fool you – this is simple home cooking at its finest. While the veggies roast (which, between you and me, is when all the magic happens), you can get everything else ready. Before you know it, you’ll have a dish that looks like you spent hours in the kitchen, but really comes together quicker than you can say “seconds please!”
What I love most is how the flavors just sing together. That little bit of smoked paprika? It’s my secret weapon – adds the perfect touch of warmth without being spicy. And trust me, even the veggie skeptics at your table will be going back for more of those caramelized Brussels sprouts!
Why You’ll Love This Sausage Pasta Brussels Sprouts Butternut Squash
Oh, where do I even start? This dish has been a family favorite for years, and here’s why:
- Hearty comfort in every bite – That perfect combo of pasta, smoky sausage, and roasted veggies makes it feel like a hug on a plate. Ideal for chilly evenings when you need something satisfying.
- Flavors that dance together – Sweet squash, slightly bitter Brussels sprouts, garlicky butter, and that hint of smoked paprika? It’s like fall decided to throw a party in your mouth!
- Almost one-pan magic – Besides boiling the pasta (which takes no time), everything comes together in the skillet – less cleanup means more time to enjoy seconds.
- Seasonal goodness – When squash and Brussels sprouts are at their peak, this dish lets them shine. Fresh ingredients make all the difference, just like my grandma taught me.
Seriously, once you try this combo, it’ll become your go-to for easy weeknights and impressive enough for company!
Ingredients for Sausage Pasta Brussels Sprouts Butternut Squash
Now, don’t you worry – I’ve kept the ingredient list simple, just like Grandma Jo would’ve wanted. Everything here works together like old friends at a potluck:

For the Roasted Veggies
- 3 cups butternut squash – peeled, seeded, and cut into ½-inch cubes (about 1 small squash)
- 12 oz Brussels sprouts – trimmed and halved (look for firm, bright green ones!)
- 3 tbsp olive oil – divided (1 tbsp for squash, 2 tbsp for sprouts)
- Salt and freshly ground black pepper – to taste (don’t be shy now!)
For the Pasta & Sausage
- 8 oz bow tie pasta – or whatever shape makes your heart happy
- 12 oz cooked smoked sausage – Andouille or Cajun-style for extra flavor, sliced into coins
- 1 tbsp olive oil – for browning that beautiful sausage
For the Garlic Butter Sauce
- 5 cloves garlic – minced (yes, five! They mellow when cooked)
- 2 tbsp butter – real butter only, please
- ¼ tsp smoked paprika (optional, but oh-so-good)
- Fresh thyme – for that pretty finish
See? Nothing too fancy, just good honest ingredients that’ll make your kitchen smell absolutely heavenly. Now let’s get cooking!
Ingredient Substitutions
Oh honey, cooking should be flexible! Here are my favorite swaps when I’m missing something:
- No Brussels sprouts? Try kale or broccoli – just roast them same as the squash.
- Not a pork fan? Chicken sausage works wonderfully, or even turkey kielbasa.
- Gluten concerns? Use your favorite gluten-free pasta – it’ll still soak up that garlic butter beautifully.
The beauty of this dish? It welcomes whatever you’ve got! If you’re looking for more ways to use up seasonal produce, check out my ideas for roasted butternut squash with feta.
How to Make Sausage Pasta Brussels Sprouts Butternut Squash
Alright, let’s get down to business! This dish comes together like a well-choreographed dance – each step simple, but timing is everything. Don’t worry, I’ll walk you through it just like I did with my grandkids when they first learned to cook.

Roasting the Vegetables
First things first – heat that oven to 400°F. While it’s warming up, toss your butternut squash cubes with 1 tablespoon olive oil, salt, and pepper on a parchment-lined baking sheet. Spread ’em out nice and even – no crowding! They need their space to caramelize properly. Pop them in the oven for about 15 minutes before adding the Brussels sprouts (tossed with 2 tablespoons oil, salt, and pepper on another sheet). The sprouts take less time, so this staggered start means everything gets perfectly tender and golden at the same time. You’ll know they’re ready when the edges get that beautiful brown crispiness.
Cooking the Pasta and Sausage
While those veggies are roasting, let’s multitask! Get your pasta water boiling – add a good pinch of salt to the water, just like Grandma Jo always said. Cook the bow ties until al dente (about a minute less than the package says), then drain but don’t rinse – we want that starch to help the sauce cling later.
Now for the sausage – heat 1 tablespoon oil in your trusty skillet over medium. Add those sliced coins and let them get a nice sear, about 5 minutes per side. You’ll know they’re ready when they’ve got some color and the kitchen smells like heaven. Scoop them out and set aside – but don’t you dare clean that skillet! All those browned bits are flavor gold.
Combining Everything
Here comes the magic! In that same skillet, add the garlic and cook just until fragrant – about a minute. Then swirl in the butter until it’s all melty and glorious. Toss in the cooked pasta, giving it a good coat in that garlic butter. Now gently fold in your roasted veggies and sausage – I like to use tongs for this part to keep everything intact. Finish with a sprinkle of smoked paprika if you’re using it, and adjust the salt and pepper to taste. Oh, and don’t forget that fresh thyme for a pretty finish!
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Yummy Sausage Pasta with Brussels Sprouts & Butternut Squash
A hearty and flavorful dish combining roasted butternut squash, Brussels sprouts, pasta, and smoked sausage in a garlic butter sauce.
- Total Time: 45 minutes
- Yield: 4 servings 1x
Ingredients
- 3 cups butternut squash, peeled, seeded, cubed
- 1 tbsp olive oil
- Salt and pepper, to taste
- 12 oz Brussels sprouts, trimmed and halved
- 2 tbsp olive oil
- 8 oz bow tie pasta
- 1 tbsp olive oil
- 12 oz cooked smoked sausage (Andouille or Cajun), sliced
- 5 cloves garlic, minced
- 2 tbsp butter
- ¼ tsp smoked paprika (optional)
- Fresh thyme, for garnish
Instructions
- Preheat oven to 400°F. Toss butternut squash with olive oil, salt, and pepper. Spread on a parchment-lined baking sheet without overcrowding. Roast 15–20 minutes, until tender and lightly golden.
- Toss Brussels sprouts with olive oil, salt, and pepper. Roast on a separate sheet (or alongside squash if there’s space) for 20–30 minutes until caramelized.
- Boil pasta according to package directions. Drain and set aside.
- Heat 1 tbsp olive oil in a large cast-iron or stainless steel skillet. Add sliced sausage and cook 5 minutes per side until lightly browned. Remove from skillet.
- In the same skillet, add garlic and cook 1–2 minutes until fragrant. Stir in butter. Add cooked pasta and toss to coat with the sauce.
- Add roasted butternut squash, roasted Brussels sprouts, sausage, and fresh thyme to the skillet. Toss gently to combine. Adjust seasoning with salt, pepper, and smoked paprika if desired.
- Serve hot, garnished with extra thyme.
Notes
- Use Andouille or Cajun sausage for extra flavor.
- Add smoked paprika for a smoky taste.
- Serve with a Fall salad or warm bread.
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Category: Main Course
- Method: Roasting, Sautéing
- Cuisine: American
- Diet: Low Lactose
Nutrition
- Serving Size: 1 serving
- Calories: 450
- Sugar: 6g
- Sodium: 800mg
- Fat: 25g
- Saturated Fat: 8g
- Unsaturated Fat: 15g
- Trans Fat: 0g
- Carbohydrates: 45g
- Fiber: 8g
- Protein: 18g
- Cholesterol: 50mg
Tips for Perfect Sausage Pasta Brussels Sprouts Butternut Squash
After making this dish more times than I can count, here are my can’t-live-without tips:

- Sausage matters! Andouille adds wonderful smoky depth, but if you’re sensitive to spice, mild Italian sausage works too. Just make sure it’s fully cooked before slicing.
- Dry those sprouts! After washing Brussels sprouts, pat them bone-dry with towels. Wet sprouts steam instead of getting beautifully caramelized.
- Garlic timing is key – cook it just until fragrant (about 60 seconds) to avoid bitterness. Burnt garlic ruins everything!
- Cut squash evenly – ½-inch cubes roast uniformly. Too big and they stay hard; too small and they turn to mush.
Follow these simple tricks, and your dish will turn out perfect every single time! If you enjoy this kind of hearty, comforting meal, you might also love my creamy smoked sausage pasta recipe.
Serving Suggestions for Sausage Pasta Brussels Sprouts Butternut Squash
Now, let’s talk about how to serve this beauty! Personally, I love pairing it with a hunk of warm, crusty bread – perfect for soaking up every last bit of that garlic butter sauce. If you’re feeling fancy, a simple apple walnut salad cuts through the richness nicely. And oh! A chilled glass of cider makes it feel extra special. Honestly though? This dish stands proud all on its own – just grab a fork and dig in!
Storage and Reheating
Now listen close – this dish keeps beautifully in the fridge for about 3 days, though I doubt it’ll last that long! When reheating, skip the microwave (makes everything soggy) and use a skillet instead. Just a quick toss over medium heat brings back that perfect crispness to the veggies and sausage. If it seems dry, add a splash of chicken broth or water to loosen it up. And here’s my little secret – sometimes I think the flavors taste even better the next day after they’ve had time to get cozy together!
Nutritional Information
Now sugar, I’m no nutritionist, but here’s the general idea per serving (and mind you, these numbers dance around based on your exact ingredients): about 450 calories, with 18g protein and a nice 8g of fiber from all those gorgeous veggies. It’s got good fats from the olive oil and loads of vitamin A from that beautiful butternut squash. Just remember – my grandma always said good food’s about more than numbers, it’s about the love you put in!
FAQs About Sausage Pasta Brussels Sprouts Butternut Squash
Over the years, I’ve gotten all sorts of questions about this recipe – here are the ones that pop up most often:
Can I use frozen butternut squash?
Oh honey, I’ve been there! Frozen squash works in a pinch, but pat it dry thoroughly before roasting. It won’t caramelize quite as nicely as fresh, but it’ll still taste delicious. Just reduce roasting time by about 5 minutes since it’s already partially cooked.
How spicy is Andouille sausage?
Andouille has a lovely smoky heat – I’d call it medium spice level. If you’re sensitive to spice, try mild Italian sausage or kielbasa instead. The smoked paprika (if using) adds just a whisper of warmth without being overpowering.
Can I make this vegetarian?
Absolutely! Skip the sausage and add extra veggies – mushrooms or chickpeas work great. For protein, toss in some white beans when combining everything. You’ll still get that wonderful roasted vegetable flavor with the garlic butter sauce.
My Brussels sprouts keep burning – help!
Two tricks: First, make sure they’re completely dry before roasting. Second, place them cut-side down on the baking sheet – this gives them that perfect caramelization without charring. And don’t crowd the pan!
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